Recent Publication List

• Botulinum Endopeptidase: SAXS Experiments and MD Simulations Reveal Extended Solution Structures That Account for Its Biochemical Properties

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• Kumar, R., Feltrup, T. M., Kukreja, R. V., Patel, K. B., Cai, S., and Singh, B. R. (2019). Evolutionary features in the structure and function of bacterial toxins. Toxins, 11, 1 - 23.

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• Dhaliwal, H. P. K., Thiruvanakarassu, N., Kumar, R., Patel, K., Ambrin, G., Cai, S., and Singh, B. R. (2018). High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics. The Protein Journal, 36, 486 – 491.

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• Neuronal Signaling Aug 31, 2018, 2 (3) NS20180058; DOI: 10.1042/NS20180058 . Therapeutic use of botulinum toxin in pain treatment. Read More Read More

• Kruti B. Patel; Shuowei Cai; B K Singh; Virender S. Parmar; Bal Ram Singh. Natural Compounds and their Analogues as Potent Antidotes against the Most Poisonous Bacterial toxin. Publisher: "Applied Environ Microbiology (AME)", Nov 2 2018, 84(24) 2018 Nov 30;84(24). pii: e01280-18. doi: 10.1128/AEM.01280-18 Read More

• Harkiranpreet Kaur Dhaliwal, Nagarajan Thiruvanakarasu, Raj Kumar, Kruti Patel, Ghuncha Ambrin, Shouwei Cai, Bal Ram Singh (2017) High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics, Publisher: "The Protein Journal", DOI 10.1007/s10930-017-9744-8.

• Kruti Patel, Shmuel Halevi, Paul Melman, John Schwartz, Shuowei Cai and Bal Ram Singh (2017) A Novel Surface Plasmon Resonance Biosensor for the Rapid Detection of Botulinum Neurotoxins, Publisher: "Biosensor", 7, 32; DOI:10.3390/bios7030032 Read More

Recent Posters

• Ravichandran E, Davis J, Wang L, Patel K, Kumar R, and Singh BR(2016). Development of recombinant protein based vaccine for BoNT. Bioscience meeting, Baltimore, June 7. . View Poster

• Fardeen Rashid, Zachary Young, Raj Kumar, and Bal Ram Singh (2015). In Silico quantitative structure-inhibition relationship (QSIR) for selected candidates against botulinum neurotoxin A light chain.

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• Raj Kumar, Wei Ping Yang, Thomas Feltrup, Guncha Ambrin, Tzuu Wang Chang, Paul Lindo, Shuowei Cai, and Bal Ram Singh (2015). Sizes and Structures of SNAP-25 substrates and botulinum neurotoxin endopeptidase influence enzyme assays. Inter Botulinum Research Coordination Committee Conference in Philadelphia. Octobet 25 – 28, 2015.

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• Raj Kumar, Olga Kononova, Shuowei Cai, Valeri Barsegov, and Bal Ram Singh (2014). Dynamic Solution Structure of BoNT/A Light Chain Critical for Binding to Potential Inhibitors. Inter Botulinum Research Coordination Committee Conference in Philadelphia, October 26-29, 2014.

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